Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredBy |
gptkb:Donald_Fredrickson
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:encodedBy |
gptkb:APOA1_gene
|
| gptkbp:foundIn |
high-density lipoprotein
|
| gptkbp:function |
cholesterol transport
activates LCAT |
| https://www.w3.org/2000/01/rdf-schema#label |
Apolipoprotein A-I
|
| gptkbp:length |
243 amino acids
|
| gptkbp:locatedOnChromosome |
chromosome 11
|
| gptkbp:molecularWeight |
28 kDa
|
| gptkbp:PDB |
2A01
|
| gptkbp:postTranslationalModification |
oxidation
glycation |
| gptkbp:significance |
associated with Tangier disease
associated with familial amyloidosis mutations cause HDL deficiency |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
amphipathic alpha-helix
|
| gptkbp:UniProtID |
P02647
|
| gptkbp:usedAs |
biomarker for cardiovascular disease
|
| gptkbp:bfsParent |
gptkb:A0G
|
| gptkbp:bfsLayer |
6
|