Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:affects |
lipid metabolism
cholesterol levels |
gptkbp:associatedWith |
gptkb:Alzheimer's_disease
increased risk of cardiovascular disease |
gptkbp:canBe |
heterozygous
homozygous |
gptkbp:foundInGene |
gptkb:APOE
|
gptkbp:frequencyHigherIn |
European populations
|
gptkbp:frequencyLowerIn |
gptkb:East_Asian_populations
|
gptkbp:hasAllele |
gptkb:APOE_ε4
|
https://www.w3.org/2000/01/rdf-schema#label |
ApoE4 genotype
|
gptkbp:impact |
cognitive decline
tau pathology amyloid-beta accumulation |
gptkbp:influenced |
response to brain injury
response to statin therapy |
gptkbp:riskFactor |
gptkb:late-onset_Alzheimer's_disease
number of ε4 alleles |
gptkbp:studiedIn |
genetic epidemiology
|
gptkbp:testedBy |
genetic testing
|
gptkbp:bfsParent |
gptkb:amyloid-related_imaging_abnormalities_(ARIA)
|
gptkbp:bfsLayer |
7
|