ApoE4 genotype

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:affects lipid metabolism
cholesterol levels
gptkbp:associatedWith gptkb:Alzheimer's_disease
increased risk of cardiovascular disease
gptkbp:canBe heterozygous
homozygous
gptkbp:foundInGene gptkb:APOE
gptkbp:frequencyHigherIn European populations
gptkbp:frequencyLowerIn gptkb:East_Asian_populations
gptkbp:hasAllele gptkb:APOE_ε4
https://www.w3.org/2000/01/rdf-schema#label ApoE4 genotype
gptkbp:impact cognitive decline
tau pathology
amyloid-beta accumulation
gptkbp:influenced response to brain injury
response to statin therapy
gptkbp:riskFactor gptkb:late-onset_Alzheimer's_disease
number of ε4 alleles
gptkbp:studiedIn genetic epidemiology
gptkbp:testedBy genetic testing
gptkbp:bfsParent gptkb:amyloid-related_imaging_abnormalities_(ARIA)
gptkbp:bfsLayer 7