Alzheimer's disease with late onset

URI: https://gptkb.org/entity/Alzheimer's_disease_with_late_onset
GPTKB entity
Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:disease
neurodegenerative disease
gptkbp:affects brain
hippocampus
gptkbp:associatedWith gptkb:CR1_gene
gptkb:APOE_gene
gptkb:CLU_gene
gptkb:PICALM_gene
gptkbp:causedBy unknown
gptkbp:complication death
malnutrition
falls
infections
loss of independence
gptkbp:differentialDiagnosis gptkb:depression
vascular dementia
Lewy body dementia
frontotemporal dementia
gptkbp:firstDescribed 1906
gptkbp:hasDiagnosticMethod clinical assessment
neuroimaging
cognitive testing
CSF biomarkers
gptkbp:hasOnsetAge 65 years or older
https://www.w3.org/2000/01/rdf-schema#label Alzheimer's disease with late onset
gptkbp:ICD-10_code gptkb:G30.1
gptkbp:MeSH_ID gptkb:D000544
gptkbp:namedAfter gptkb:Alois_Alzheimer
gptkbp:OMIM 104300
gptkbp:pathology amyloid plaques
neurofibrillary tangles
gptkbp:prevalence most common form of dementia
gptkbp:prognosis progressive
incurable
gptkbp:riskFactor gptkb:cardiovascular_disease
gptkb:diabetes
gptkb:APOE_ε4_allele
age
family history
smoking
hypertension
low physical activity
gptkbp:subspecies gptkb:Alzheimer's_disease
gptkbp:symptom cognitive decline
disorientation
memory loss
language problems
impaired judgment
gptkbp:treatment gptkb:memantine
acetylcholinesterase inhibitors
supportive care
gptkbp:bfsParent gptkb:G30.1
gptkbp:bfsLayer 7