|
gptkbp:instanceOf
|
neurodegenerative disease
|
|
gptkbp:affects
|
brain
|
|
gptkbp:alsoKnownAs
|
gptkb:AD
|
|
gptkbp:associatedWith
|
gptkb:tau_protein
gptkb:beta-amyloid
amyloid plaques
neurofibrillary tangles
|
|
gptkbp:category
|
gptkb:dementia
neurological disorder
progressive disease
|
|
gptkbp:cause
|
unknown
|
|
gptkbp:complication
|
death
loss of independence
|
|
gptkbp:diagnosedBy
|
brain imaging
clinical assessment
neuropsychological tests
biomarker tests
|
|
gptkbp:earlyOnset
|
possible before age 65
|
|
gptkbp:firstDescribed
|
gptkb:Alois_Alzheimer
1906
|
|
gptkbp:hasNoCure
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Alzheimer's Disease
|
|
gptkbp:ICD-10_code
|
gptkb:G30
|
|
gptkbp:MeSH_ID
|
gptkb:D000544
|
|
gptkbp:namedAfter
|
gptkb:Alois_Alzheimer
|
|
gptkbp:OMIM
|
104300
|
|
gptkbp:onset
|
usually after age 65
|
|
gptkbp:prevalence
|
affects millions worldwide
most common cause of dementia
|
|
gptkbp:primarySymptom
|
behavioral changes
cognitive decline
memory loss
|
|
gptkbp:prognosis
|
progressive
incurable
|
|
gptkbp:researchInterest
|
biomarkers
disease-modifying therapies
genetics
prevention
|
|
gptkbp:riskFactor
|
gptkb:APOE-e4_allele
gptkb:cardiovascular_disease
age
family history
genetics
head injury
|
|
gptkbp:treatment
|
gptkb:memantine
acetylcholinesterase inhibitors
supportive care
|
|
gptkbp:bfsParent
|
gptkb:Chronic_Conditions
gptkb:Smell_Memory
|
|
gptkbp:bfsLayer
|
8
|