Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
recombinant coagulation factor IX |
| gptkbp:approvalYear |
2014
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
gptkb:B02BD09
|
| gptkbp:brand |
gptkb:Alprolix
|
| gptkbp:CASNumber |
1331326-41-4
|
| gptkbp:contains |
gptkb:factor_IX
Fc region of IgG1 |
| gptkbp:developer |
gptkb:Biogen
Swedish Orphan Biovitrum |
| gptkbp:form |
powder for solution for injection
|
| gptkbp:halfLife |
long-acting
|
| https://www.w3.org/2000/01/rdf-schema#label |
Alprolix
|
| gptkbp:indication |
perioperative management in hemophilia B
prevention of bleeding in hemophilia B treatment of bleeding episodes in hemophilia B |
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
replaces missing or defective factor IX
|
| gptkbp:pregnancyCategory |
C
|
| gptkbp:product |
gptkb:protein
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:UNII |
6B8T0X673S
|
| gptkbp:usedFor |
gptkb:hemophilia_B
|
| gptkbp:bfsParent |
gptkb:Bioverativ
gptkb:Sobi |
| gptkbp:bfsLayer |
7
|