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gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:abbreviation
|
gptkb:ALT
gptkb:SGPT
|
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gptkbp:CASNumber
|
9000-86-6
|
|
gptkbp:catalyzes
|
transamination of alanine and α-ketoglutarate to pyruvate and glutamate
|
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gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
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gptkbp:EC_number
|
2.6.1.2
|
|
gptkbp:elevatedIn
|
myocardial infarction
cirrhosis
hepatitis
liver damage
|
|
gptkbp:foundIn
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gptkb:skeletal_muscle
gptkb:kidney
heart
liver
|
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gptkbp:gene
|
gptkb:GPT
|
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gptkbp:GO_term
|
GO:0004021
|
|
gptkbp:hasBiomarker
|
liver function
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Alanine aminotransferase
|
|
gptkbp:inhibitedBy
|
gptkb:aminooxyacetate
|
|
gptkbp:measures
|
blood tests
|
|
gptkbp:molecularWeight
|
approximately 54 kDa
|
|
gptkbp:orthologInMouse
|
Gpt
|
|
gptkbp:product
|
gptkb:pyruvate
gptkb:L-glutamate
|
|
gptkbp:significance
|
indicator of hepatocellular injury
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:2-oxoglutarate
L-alanine
|
|
gptkbp:systematicName
|
gptkb:L-alanine:2-oxoglutarate_aminotransferase
|
|
gptkbp:UniProtID
|
P24298 (human)
|
|
gptkbp:bfsParent
|
gptkb:Aminotransferase
|
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gptkbp:bfsLayer
|
7
|