subependymal giant cell astrocytoma
GPTKB entity
Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
brain tumor
glioma |
gptkbp:age |
children
young adults |
gptkbp:associatedWith |
gptkb:tuberous_sclerosis_complex
|
gptkbp:cellOrigin |
astrocyte
|
gptkbp:firstDescribed |
1955
|
gptkbp:growthForm |
slow-growing
|
gptkbp:histology |
large gemistocytic cells
|
https://www.w3.org/2000/01/rdf-schema#label |
subependymal giant cell astrocytoma
|
gptkbp:ICD-10_code |
D43.0
|
gptkbp:location |
lateral ventricles
subependymal region |
gptkbp:riskFactor |
mutation in TSC1 gene
mutation in TSC2 gene |
gptkbp:signature |
enhancing mass near foramen of Monro
|
gptkbp:symptom |
hydrocephalus
increased intracranial pressure |
gptkbp:treatment |
mTOR inhibitors
surgical resection |
gptkbp:WHO_grade |
grade I
|
gptkbp:bfsParent |
gptkb:Afinitor
|
gptkbp:bfsLayer |
5
|