Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Adhesion G protein-coupled receptors
Class B2 GPCRs |
| gptkbp:characteristicDomain |
GPCR-Autoproteolysis INducing (GAIN) domain
long N-terminal extracellular region |
| gptkbp:contains |
seven transmembrane domains
autoproteolytic site |
| gptkbp:discoveredIn |
late 1990s
|
| gptkbp:encodedBy |
ADGR genes
|
| gptkbp:example |
ADGRB1
ADGRE1 ADGRG1 ADGRL1 |
| gptkbp:foundIn |
gptkb:metazoans
|
| gptkbp:function |
signal transduction
cell adhesion |
| https://www.w3.org/2000/01/rdf-schema#label |
Adhesion GPCRs
|
| gptkbp:involvedIn |
cell migration
immune response nervous system development tumorigenesis synapse formation |
| gptkbp:numberOfMembers |
over 30 in humans
|
| gptkbp:reviewedBy |
PMID: 24631297
PMID: 25193262 |
| gptkbp:subclassOf |
gptkb:G_protein-coupled_receptors
|
| gptkbp:bfsParent |
gptkb:G_protein-coupled_receptor
|
| gptkbp:bfsLayer |
5
|