|
gptkbp:instanceOf
|
nucleoside
|
|
gptkbp:ATCCode
|
C01EB10
|
|
gptkbp:CASNumber
|
58-61-7
|
|
gptkbp:chemicalFormula
|
C10H13N5O4
|
|
gptkbp:contraindication
|
gptkb:sick_sinus_syndrome
gptkb:second-_or_third-degree_AV_block
bronchospastic lung disease
|
|
gptkbp:discoveredBy
|
gptkb:Albrecht_Kossel
|
|
gptkbp:discoveredIn
|
1891
|
|
gptkbp:effect
|
central nervous system
heart rate
sleep regulation
|
|
gptkbp:eliminationHalfLife
|
<10 seconds
|
|
gptkbp:enemyOf
|
gptkb:theophylline
caffeine
theobromine
|
|
gptkbp:foundIn
|
all living cells
|
|
gptkbp:hasComponent
|
adenine
ribose
|
|
gptkbp:hasReceptor
|
A2A receptor
A2B receptor
A1 receptor
A3 receptor
|
|
gptkbp:hasUNII
|
K72T3FS567
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Adenosine
|
|
gptkbp:IUPACName
|
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
|
|
gptkbp:KEGGID
|
C00212
|
|
gptkbp:meltingPoint
|
234–236 °C
|
|
gptkbp:MeSH_ID
|
D000255
|
|
gptkbp:metabolism
|
gptkb:adenosine_deaminase
gptkb:adenosine_kinase
|
|
gptkbp:molecularWeight
|
267.24 g/mol
|
|
gptkbp:predecessor
|
gptkb:adenosine_triphosphate
gptkb:cyclic_adenosine_monophosphate
gptkb:adenosine_diphosphate
adenosine monophosphate
|
|
gptkbp:PubChem_CID
|
16335
60961
DB00640
|
|
gptkbp:roleInBiology
|
neurotransmitter
vasodilator
component of ATP
component of RNA
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
shortness of breath
chest pain
hypotension
flushing
|
|
gptkbp:solubility
|
83 mg/mL
|
|
gptkbp:usedAs
|
antiarrhythmic agent
|
|
gptkbp:usedIn
|
paroxysmal supraventricular tachycardia treatment
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:C00243
|
|
gptkbp:bfsLayer
|
6
|