Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:activeIngredient |
corticotropin
|
| gptkbp:approvalYear |
1952
|
| gptkbp:ATCCode |
H01AA01
|
| gptkbp:blackBoxWarning |
yes
|
| gptkbp:brand |
repository corticotropin injection
|
| gptkbp:broadcastOn |
prescription only
|
| gptkbp:color |
milky white
|
| gptkbp:contraindication |
gptkb:bone
gptkb:Cushing's_syndrome congestive heart failure hypertension peptic ulcer scleroderma systemic fungal infections recent surgery ocular herpes simplex primary adrenocortical insufficiency recent vaccination |
| gptkbp:FDAApproved |
yes
|
| gptkbp:form |
multi-dose vial
injectable gel |
| gptkbp:halfLife |
variable
|
| https://www.w3.org/2000/01/rdf-schema#label |
Acthar Gel
|
| gptkbp:indication |
gptkb:systemic_lupus_erythematosus
gptkb:Crohn's_disease gptkb:psoriatic_arthritis ulcerative colitis rheumatoid arthritis respiratory diseases nephrotic syndrome juvenile rheumatoid arthritis infantile spasms polymyositis sarcoidosis dermatologic diseases multiple sclerosis exacerbations ophthalmic diseases allergic states edematous states |
| gptkbp:legalStatus |
Rx-only
|
| gptkbp:manufacturer |
gptkb:Mallinckrodt_Pharmaceuticals
|
| gptkbp:marketedIn |
gptkb:United_States
|
| gptkbp:mechanismOfAction |
stimulates adrenal cortex to secrete cortisol and other corticosteroids
|
| gptkbp:NDCCode |
63004-8710-01
|
| gptkbp:pregnancyCategory |
C
|
| gptkbp:prescriptionRequired |
yes
|
| gptkbp:priceRange |
very high
|
| gptkbp:routeOfAdministration |
intramuscular injection
subcutaneous injection |
| gptkbp:sideEffect |
gptkb:bone
edema hypertension mood changes weight gain insomnia hyperglycemia infection risk |
| gptkbp:soldIn |
gptkb:European_Union
|
| gptkbp:storage |
refrigerate
|
| gptkbp:website |
https://www.acthar.com/
|
| gptkbp:bfsParent |
gptkb:Mallinckrodt_Pharmaceuticals
gptkb:Mallinckrodt |
| gptkbp:bfsLayer |
7
|