|
gptkbp:instanceOf
|
antiretroviral therapy
protease inhibitor
|
|
gptkbp:administeredBy
|
oral route
intravenous route
|
|
gptkbp:affiliatedWith
|
gptkb:World_Health_Organization's_List_of_Essential_Medicines
|
|
gptkbp:approved_for_use_in
|
1987
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J05AF01
|
|
gptkbp:CASNumber
|
30516-87-1
|
|
gptkbp:chemicalFormula
|
C10H13N5O4
|
|
gptkbp:developedBy
|
gptkb:Jerome_Horwitz
|
|
gptkbp:discoveredBy
|
gptkb:Michigan_Cancer_Foundation
1964
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:excretion
|
kidneys
|
|
gptkbp:first_antiretroviral_approved_for_HIV
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AZT (zidovudine)
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
gptkb:Retrovir
|
|
gptkbp:mechanismOfAction
|
inhibits reverse transcriptase
|
|
gptkbp:MeSH_ID
|
D015215
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
267.24 g/mol
|
|
gptkbp:originally_developed_for
|
gptkb:cancer
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
35370
|
|
gptkbp:sideEffect
|
gptkb:anemia
nausea
headache
neutropenia
|
|
gptkbp:synonym
|
gptkb:3'-azido-3'-deoxythymidine
gptkb:ZDV
gptkb:azidothymidine
|
|
gptkbp:UNII
|
4B9XT59T7S
|
|
gptkbp:usedFor
|
gptkb:AIDS
HIV infection
|
|
gptkbp:bfsParent
|
gptkb:Burroughs_Wellcome
gptkb:Burroughs_Wellcome_Company
|
|
gptkbp:bfsLayer
|
6
|