Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antiviral drug |
| gptkbp:administeredBy |
oral
intravenous |
| gptkbp:approvedBy |
gptkb:FDA
1987 |
| gptkbp:ATCCode |
J05AF01
|
| gptkbp:bioavailability |
60-70%
|
| gptkbp:CASNumber |
30516-87-1
|
| gptkbp:developedBy |
gptkb:Burroughs_Wellcome
|
| gptkbp:discoveredIn |
1964
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:hasMolecularFormula |
C10H13N5O4
|
| gptkbp:hasSMILES |
CC1=CN(C(=O)NC1=O)[C@H]2O[C@@H](N=[N+]=[N-])[C@H](CO)O2
|
| gptkbp:hasUNII |
W4X6EY9V0B
|
| https://www.w3.org/2000/01/rdf-schema#label |
3'-azido-3'-deoxythymidine
|
| gptkbp:IUPACName |
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
|
| gptkbp:mechanismOfAction |
reverse transcriptase inhibitor
|
| gptkbp:meltingPoint |
125°C
|
| gptkbp:metabolism |
liver
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL137
35370 DB00495 |
| gptkbp:sideEffect |
gptkb:anemia
nausea headache neutropenia |
| gptkbp:synonym |
gptkb:AZT
gptkb:zidovudine |
| gptkbp:usedFor |
HIV treatment
|
| gptkbp:bfsParent |
gptkb:AZT
|
| gptkbp:bfsLayer |
6
|