Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredBy |
gptkb:Jens_Christian_Skou
|
| gptkbp:discoveredIn |
1957
|
| gptkbp:example |
gptkb:dynein
gptkb:myosin gptkb:kinesin helicase ABC transporter ATPase Ca2+-ATPase F-type ATPase H+/K+-ATPase Na+/K+-ATPase V-type ATPase chaperonin |
| gptkbp:foundIn |
all domains of life
|
| gptkbp:function |
catalyze hydrolysis of ATP
|
| gptkbp:GO_term |
GO:0016887 (ATPase activity)
|
| https://www.w3.org/2000/01/rdf-schema#label |
ATPase proteins
|
| gptkbp:inhibitedBy |
ouabain (for Na+/K+-ATPase)
vanadate (for P-type ATPases) |
| gptkbp:mechanismOfAction |
conformational change upon ATP binding/hydrolysis
hydrolyze ATP to ADP and phosphate |
| gptkbp:NobelPrizeYear |
1997 (Jens Christian Skou)
|
| gptkbp:powerSource |
gptkb:ATP
|
| gptkbp:role |
vesicle trafficking
DNA replication protein folding muscle contraction active transport cell motility ion transport energy transduction |
| gptkbp:structure |
often have nucleotide-binding domains
often have transmembrane domains (in transporters) |
| gptkbp:bfsParent |
gptkb:Walker_B_motif
gptkb:arginine_finger |
| gptkbp:bfsLayer |
7
|