|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
desnutrin
iPLA2ζ
patatin-like phospholipase domain-containing protein 2
|
|
gptkbp:associatedWith
|
gptkb:neutral_lipid_storage_disease_with_myopathy
|
|
gptkbp:discoveredBy
|
Zimmermann et al.
|
|
gptkbp:discoveredIn
|
2004
|
|
gptkbp:EC_number
|
3.1.1.3
|
|
gptkbp:encodedBy
|
gptkb:PNPLA2_gene
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
heart
adipose tissue
|
|
gptkbp:fullName
|
Adipose triglyceride lipase
|
|
gptkbp:function
|
catalyzes the hydrolysis of triglycerides
initiates lipolysis
|
|
gptkbp:gene
|
gptkb:PNPLA2
|
|
gptkbp:GO_term
|
GO:0004806
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATGL
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:location
|
gptkb:cytoplasm
lipid droplet
|
|
gptkbp:molecularWeight
|
54 kDa
|
|
gptkbp:OMIM
|
609059
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
6QK8
|
|
gptkbp:regulates
|
activated by CGI-58
inhibited by G0S2
|
|
gptkbp:UniProtID
|
gptkb:Q96AD5
|
|
gptkbp:bfsParent
|
gptkb:AMPK_pathway
|
|
gptkbp:bfsLayer
|
6
|