|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:agouti_signaling_protein
agouti
nonagouti
|
|
gptkbp:associatedWith
|
gptkb:type_2_diabetes
obesity
coat color variation
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:enemyOf
|
gptkb:MC1R
|
|
gptkbp:Entrez_Gene_ID
|
434
ENSG00000181544
|
|
gptkbp:expressedIn
|
gptkb:skin
adipose tissue
|
|
gptkbp:fullName
|
gptkb:Agouti_Signaling_Protein
|
|
gptkbp:function
|
antagonist of melanocortin 1 receptor (MC1R)
regulates melanogenesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:739
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ASIP gene
|
|
gptkbp:length
|
131 amino acids (human protein)
|
|
gptkbp:locatedOnChromosome
|
20
|
|
gptkbp:location
|
20q11.22
|
|
gptkbp:mutationAssociatedWith
|
can cause altered pigmentation
can influence risk of obesity
|
|
gptkbp:OMIM
|
600201
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Agouti gene
|
|
gptkbp:pathway
|
melanogenesis pathway
|
|
gptkbp:product
|
ASIP protein
|
|
gptkbp:regulates
|
melanin synthesis
|
|
gptkbp:symbol
|
gptkb:ASIP
|
|
gptkbp:UniProtID
|
gptkb:P42127
|
|
gptkbp:bfsParent
|
gptkb:Agouti_Signaling_Protein
gptkb:agouti_gene
|
|
gptkbp:bfsLayer
|
7
|