Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affects |
coat color
|
| gptkbp:alternativeName |
gptkb:ASIP
|
| gptkbp:associatedWith |
pigmentation disorders
|
| gptkbp:binds |
gptkb:melanocortin_1_receptor
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:ASIP_gene
|
| gptkbp:expressedIn |
gptkb:skin
adipose tissue |
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
antagonist of melanocortin receptors
|
| https://www.w3.org/2000/01/rdf-schema#label |
Agouti Signaling Protein
|
| gptkbp:inhibitedBy |
alpha-MSH signaling
|
| gptkbp:length |
132 amino acids (human)
|
| gptkbp:locatedOnChromosome |
gptkb:human_chromosome_20
|
| gptkbp:orthologIn |
gptkb:mouse_agouti_protein
|
| gptkbp:regulates |
melanin production
|
| gptkbp:relatedTo |
obesity in mice
yellow fur in mice |
| gptkbp:structure |
contains cysteine-rich domain
|
| gptkbp:UniProtID |
gptkb:P42127
|
| gptkbp:bfsParent |
gptkb:ASIP
|
| gptkbp:bfsLayer |
6
|