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gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:alternativeName
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gptkb:ALT
gptkb:SGPT
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gptkbp:cofactor
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gptkb:pyridoxal_phosphate
|
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gptkbp:decreasedIn
|
gptkb:vitamin_B6_deficiency
|
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gptkbp:EC_number
|
2.6.1.2
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gptkbp:foundIn
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gptkb:skeletal_muscle
gptkb:kidney
heart
liver
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gptkbp:fullName
|
gptkb:alanine_aminotransferase
|
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gptkbp:function
|
catalyzes the transfer of amino groups from alanine to alpha-ketoglutarate
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gptkbp:gene
|
gptkb:GPT
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ASA(ALT)
|
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gptkbp:improves
|
gptkb:non-alcoholic_fatty_liver_disease
hepatitis
alcoholic liver disease
drug-induced liver injury
muscle injury
|
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gptkbp:measures
|
blood serum
|
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gptkbp:molecularWeight
|
approximately 55 kDa
|
|
gptkbp:product
|
gptkb:pyruvate
gptkb:L-glutamate
|
|
gptkbp:range
|
7-56 units per liter (U/L) in adults
|
|
gptkbp:significance
|
elevated levels indicate liver damage
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:alpha-ketoglutarate
L-alanine
|
|
gptkbp:usedIn
|
liver function tests
|
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gptkbp:bfsParent
|
gptkb:Assistant_Secretary_of_the_Army_(Acquisition,_Logistics_and_Technology)
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gptkbp:bfsLayer
|
7
|