|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:abbreviation
|
gptkb:ALT
|
|
gptkbp:alternativeName
|
gptkb:serum_glutamic-pyruvic_transaminase
|
|
gptkbp:CASNumber
|
9000-86-6
|
|
gptkbp:catalyzes
|
transamination of alanine and α-ketoglutarate to pyruvate and glutamate
|
|
gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
|
gptkbp:decreasedLevelIndicates
|
gptkb:vitamin_B6_deficiency
|
|
gptkbp:EC_number
|
2.6.1.2
|
|
gptkbp:enzymeClassification
|
transferase
|
|
gptkbp:firstDescribed
|
1955
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
gptkb:kidney
heart
liver
|
|
gptkbp:gene
|
gptkb:GPT
|
|
gptkbp:GO_term
|
GO:0004021
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
alanine aminotransferase
|
|
gptkbp:increasedLevelIndicates
|
liver injury
|
|
gptkbp:inhibitedBy
|
gptkb:aminooxyacetate
|
|
gptkbp:measures
|
blood tests
|
|
gptkbp:molecularWeight
|
approximately 54 kDa
|
|
gptkbp:orthologIn
|
found in many species
|
|
gptkbp:product
|
gptkb:pyruvate
gptkb:L-glutamate
|
|
gptkbp:significance
|
marker for liver damage
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:α-ketoglutarate
L-alanine
|
|
gptkbp:UniProtID
|
gptkb:P24298
|
|
gptkbp:usedIn
|
diagnosis of hepatitis
monitoring liver disease
|
|
gptkbp:bfsParent
|
gptkb:ALT
gptkb:pyridoxal_phosphate
|
|
gptkbp:bfsLayer
|
7
|