ARCUS genome editing technology
GPTKB entity
Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
genome editing technology
|
gptkbp:basedOn |
meganuclease
|
gptkbp:contrastsWith |
gptkb:CRISPR
gptkb:TALEN gptkb:ZFNs |
gptkbp:developedBy |
Precision BioSciences
|
gptkbp:distinctiveFeature |
high specificity
minimal off-target effects small size of editing enzyme |
gptkbp:enables |
gene knockout
gene correction gene insertion precise DNA deletion precise DNA insertion precise DNA repair |
gptkbp:firstDescribed |
2010s
|
https://www.w3.org/2000/01/rdf-schema#label |
ARCUS genome editing technology
|
gptkbp:mechanismOfAction |
double-strand DNA break
|
gptkbp:patent |
Precision BioSciences
|
gptkbp:targetSequence |
specific DNA sequences
|
gptkbp:usedFor |
therapeutic genome editing
crop improvement |
gptkbp:usedIn |
gptkb:agricultural_machinery
gene therapy |
gptkbp:uses |
engineered homing endonucleases
|
gptkbp:bfsParent |
gptkb:Precision_Biosciences
|
gptkbp:bfsLayer |
7
|