Statements (13)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:apurinic/apyrimidinic_endonuclease
|
gptkbp:catalyzes |
cleavage of DNA at apurinic/apyrimidinic sites
|
gptkbp:EC_number |
4.2.99.18
|
gptkbp:foundIn |
gptkb:Bacteria
eukaryotes |
https://www.w3.org/2000/01/rdf-schema#label |
AP lyase
|
gptkbp:involvedIn |
base excision repair
|
gptkbp:mechanismOfAction |
beta-elimination
|
gptkbp:product |
DNA strand break with 3'-phospho-alpha,beta-unsaturated aldehyde end
|
gptkbp:substrate |
abasic DNA site
|
gptkbp:bfsParent |
gptkb:AP_endonuclease
|
gptkbp:bfsLayer |
7
|