AP lyase

GPTKB entity

Statements (13)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:apurinic/apyrimidinic_endonuclease
gptkbp:catalyzes cleavage of DNA at apurinic/apyrimidinic sites
gptkbp:EC_number 4.2.99.18
gptkbp:foundIn gptkb:Bacteria
eukaryotes
https://www.w3.org/2000/01/rdf-schema#label AP lyase
gptkbp:involvedIn base excision repair
gptkbp:mechanismOfAction beta-elimination
gptkbp:product DNA strand break with 3'-phospho-alpha,beta-unsaturated aldehyde end
gptkbp:substrate abasic DNA site
gptkbp:bfsParent gptkb:AP_endonuclease
gptkbp:bfsLayer 7