ANGPT2

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:cancer
sepsis
diabetic retinopathy
gptkbp:component extracellular space
gptkbp:discoveredIn 1997
gptkbp:encodes angiopoietin-2 protein
gptkbp:Entrez_Gene_ID 285
ENSG00000114739
gptkbp:expressedIn endothelial cells
gptkbp:fullName angiopoietin 2
gptkbp:function regulation of angiogenesis
growth factor activity
vascular development
gptkbp:GOProcess angiogenesis
gptkbp:HGNC_ID HGNC:484
https://www.w3.org/2000/01/rdf-schema#label ANGPT2
gptkbp:interactsWith TIE2 receptor
gptkbp:length 496 amino acids
gptkbp:locatedOnChromosome 8
8p23.1
gptkbp:molecularWeight 57 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Angpt2
gptkbp:proteinFamily angiopoietin family
gptkbp:regulates upregulated by hypoxia
vascular permeability
endothelial cell survival
regulated by VEGF
gptkbp:UniProtID O15123
gptkbp:bfsParent gptkb:angiopoietin-2
gptkbp:bfsLayer 7