|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:AMP
gptkb:ADP
phosphorylation
|
|
gptkbp:alternativeName
|
gptkb:AMPK_catalytic_subunit_alpha-2
|
|
gptkbp:associatedWith
|
gptkb:cardiovascular_disease
gptkb:type_2_diabetes
|
|
gptkbp:component
|
gptkb:AMP-activated_protein_kinase
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.31
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
heart
liver
|
|
gptkbp:formsComplexWith
|
AMPK beta subunit
AMPK gamma subunit
|
|
gptkbp:function
|
catalytic subunit of AMPK
|
|
gptkbp:gene
|
gptkb:PRKAA2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AMPK alpha2
|
|
gptkbp:inhibitedBy
|
gptkb:ATP
|
|
gptkbp:involves
|
cellular energy homeostasis
|
|
gptkbp:locatedOnChromosome
|
1p31
|
|
gptkbp:molecularWeight
|
~63 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Prkaa2
|
|
gptkbp:phosphorylates
|
Thr172
|
|
gptkbp:regulates
|
glucose uptake
fatty acid oxidation
mitochondrial biogenesis
|
|
gptkbp:subunit_type
|
catalytic alpha subunit
|
|
gptkbp:UniProtID
|
gptkb:Q9Y478
|
|
gptkbp:bfsParent
|
gptkb:PRKAA2
|
|
gptkbp:bfsLayer
|
7
|