|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
AAA-plus protein family
|
|
gptkbp:domain
|
AAA+ domain
|
|
gptkbp:firstDescribed
|
1990s
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
eukaryotes
|
|
gptkbp:fullName
|
gptkb:ATPases_Associated_with_diverse_cellular_Activities_protein_family
|
|
gptkbp:function
|
DNA replication
protein degradation
protein unfolding
ATPase activity
membrane fusion
protein disaggregation
|
|
gptkbp:GO_term
|
GO:0042623
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AAA+ protein family
|
|
gptkbp:InterPro
|
gptkb:IPR003593
|
|
gptkbp:mechanismOfAction
|
conformational changes
hexameric ring formation
|
|
gptkbp:notable_member
|
gptkb:NSF
gptkb:p97/VCP
gptkb:proteasome_regulatory_particle
gptkb:ClpA
gptkb:ClpB
gptkb:ClpX
gptkb:Hsp104
gptkb:MCM_complex
|
|
gptkbp:powerSource
|
ATP hydrolysis
|
|
gptkbp:proteinFamily
|
gptkb:PF00004
|
|
gptkbp:relatedTo
|
AAA protein family
|
|
gptkbp:structural_feature
|
gptkb:Walker_A_motif
gptkb:Walker_B_motif
gptkb:arginine_finger
|
|
gptkbp:superfamily
|
gptkb:P-loop_NTPase_superfamily
|
|
gptkbp:bfsParent
|
gptkb:AAA_(protein_family)
|
|
gptkbp:bfsLayer
|
6
|