Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antiviral drug antineoplastic agent |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01BC08
|
| gptkbp:CASNumber |
2353-33-5
|
| gptkbp:discoveredBy |
1964
|
| gptkbp:hasInChIKey |
BZQFBWGGLSGISF-GQCTYLIASA-N
|
| gptkbp:hasMolecularFormula |
gptkb:C8H12N4O4
|
| gptkbp:hasSMILES |
C1=NC(=O)N(C(=N1)N)C2C(C(C(O2)CO)O)O
|
| gptkbp:hasUNII |
P288Z8OX4D
|
| https://www.w3.org/2000/01/rdf-schema#label |
5-aza-2'-deoxycytidine
|
| gptkbp:IUPACName |
4-amino-1-β-D-2-deoxyribofuranosyl-1,3,5-triazin-2(1H)-one
|
| gptkbp:mechanismOfAction |
DNA methyltransferase inhibitor
|
| gptkbp:meltingPoint |
230-240°C
|
| gptkbp:molecularWeight |
228.21 g/mol
|
| gptkbp:notableDerivative |
cytidine
|
| gptkbp:PubChem_CID |
451668
397963 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
gptkb:pneumonia
gptkb:anemia fever nausea vomiting diarrhea edema constipation dizziness fatigue headache hypertension cough chest pain rash elevated liver enzymes hypokalemia insomnia neutropenia hypotension thrombocytopenia dyspnea arthralgia hyperglycemia myalgia renal impairment hyperkalemia hypomagnesemia hypocalcemia |
| gptkbp:synonym |
gptkb:decitabine
|
| gptkbp:usedFor |
gptkb:acute_myeloid_leukemia
myelodysplastic syndromes |
| gptkbp:bfsParent |
gptkb:decitabine
|
| gptkbp:bfsLayer |
8
|