|
gptkbp:instanceOf
|
gptkb:antiviral_drug
gptkb:chemical_compound
gptkb:antineoplastic_agent
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
L01BC08
|
|
gptkbp:CASNumber
|
2353-33-5
|
|
gptkbp:discoveredBy
|
1964
|
|
gptkbp:hasInChIKey
|
BZQFBWGGLSGISF-GQCTYLIASA-N
|
|
gptkbp:hasMolecularFormula
|
gptkb:C8H12N4O4
|
|
gptkbp:hasSMILES
|
C1=NC(=O)N(C(=N1)N)C2C(C(C(O2)CO)O)O
|
|
gptkbp:hasUNII
|
P288Z8OX4D
|
|
gptkbp:IUPACName
|
4-amino-1-β-D-2-deoxyribofuranosyl-1,3,5-triazin-2(1H)-one
|
|
gptkbp:mechanismOfAction
|
gptkb:DNA_methyltransferase_inhibitor
|
|
gptkbp:meltingPoint
|
230-240°C
|
|
gptkbp:molecularWeight
|
228.21 g/mol
|
|
gptkbp:notableDerivative
|
cytidine
|
|
gptkbp:PubChem_CID
|
451668
397963
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
gptkb:pneumonia
gptkb:anemia
fever
nausea
vomiting
diarrhea
edema
constipation
dizziness
fatigue
headache
hypertension
cough
chest pain
rash
elevated liver enzymes
hypokalemia
insomnia
neutropenia
hypotension
thrombocytopenia
dyspnea
arthralgia
hyperglycemia
myalgia
renal impairment
hyperkalemia
hypomagnesemia
hypocalcemia
|
|
gptkbp:synonym
|
gptkb:decitabine
|
|
gptkbp:usedFor
|
gptkb:acute_myeloid_leukemia
myelodysplastic syndromes
|
|
gptkbp:bfsParent
|
gptkb:decitabine
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
5-aza-2'-deoxycytidine
|