Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:component |
microtubule
|
| gptkbp:conservedIn |
animals
fungi plants |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
gptkb:TUBA1A
TUBA1B TUBA1C TUBA3C TUBA3D TUBA4A TUBA8 |
| gptkbp:formsHeterodimerWith |
β-tubulin
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
cell division
cytoskeleton organization intracellular transport |
| gptkbp:GO |
GO:0005884
|
| gptkbp:hasIsoform |
gptkb:TUBA1A
TUBA1B TUBA1C TUBA3C TUBA3D TUBA4A TUBA8 |
| https://www.w3.org/2000/01/rdf-schema#label |
α-tubulin
|
| gptkbp:interactsWith |
motor proteins
microtubule-associated proteins |
| gptkbp:locale |
gptkb:cytoplasm
cilia flagella mitotic spindle |
| gptkbp:molecularWeight |
~50 kDa
|
| gptkbp:PDB |
1TUB
|
| gptkbp:postTranslationalModification |
acetylation
detyrosination polyglutamylation polyglycylation tyrosination |
| gptkbp:proteinFamily |
tubulin superfamily
|
| gptkbp:requires |
chromosome segregation
cell shape maintenance organelle movement |
| gptkbp:structure |
globular protein
|
| gptkbp:target |
gptkb:taxol
gptkb:vinblastine colchicine antimitotic drugs nocodazole |
| gptkbp:UniProtID |
P68363
|
| gptkbp:bfsParent |
gptkb:SIRT2
|
| gptkbp:bfsLayer |
8
|