|
gptkbp:instanceOf
|
gptkb:drug
sedative
|
|
gptkbp:approvedBy
|
1986
|
|
gptkbp:ATCCode
|
N05CF01
|
|
gptkbp:availableOn
|
gptkb:tablet
oral solution
|
|
gptkbp:brand
|
gptkb:Imovane
gptkb:Zimovane
gptkb:Zopitan
|
|
gptkbp:CASNumber
|
43200-80-2
|
|
gptkbp:chemicalFormula
|
contains a pyrrolopyrazine ring
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
respiratory failure
sleep apnea
severe liver impairment
|
|
gptkbp:controlledSubstanceSchedule
|
gptkb:Class_C_(UK)
Schedule IV (US)
|
|
gptkbp:developedBy
|
gptkb:Rhône-Poulenc
|
|
gptkbp:drugClass
|
cyclopyrrolone
|
|
gptkbp:eliminationHalfLife
|
about 5 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasMolecularFormula
|
C17H17ClN6O3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
zopiclone
|
|
gptkbp:interactsWith
|
gptkb:beer
gptkb:CNS_depressants
CYP3A4 inhibitors
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
modulates GABA-A receptor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notRecommendedFor
|
children
pregnant women
breastfeeding women
|
|
gptkbp:overdoseSymptoms
|
death
coma
respiratory depression
|
|
gptkbp:pregnancyCategory
|
gptkb:C_(Australia)
C (US)
|
|
gptkbp:relatedTo
|
gptkb:eszopiclone
gptkb:zolpidem
gptkb:zaleplon
|
|
gptkbp:riskFactor
|
tolerance
dependence
withdrawal symptoms
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gptkb:center
dizziness
headache
drowsiness
dry mouth
bitter taste
dependence
|
|
gptkbp:usedFor
|
treatment of insomnia
|
|
gptkbp:bfsParent
|
gptkb:Eszopiclone
gptkb:Z-drugs
gptkb:z-drugs
|
|
gptkbp:bfsLayer
|
7
|