Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
leukotriene receptor antagonist |
| gptkbp:approvalYear |
1996
|
| gptkbp:ATCCode |
R03DC01
|
| gptkbp:brand |
Accolate
|
| gptkbp:CASNumber |
107753-78-6
|
| gptkbp:category |
anti-asthmatic agent
|
| gptkbp:chemicalFormula |
C31H33N5O6S
|
| gptkbp:contraindication |
hepatic impairment
|
| gptkbp:developer |
gptkb:AstraZeneca
|
| gptkbp:eliminationHalfLife |
10 hours
|
| gptkbp:excretion |
feces
|
| https://www.w3.org/2000/01/rdf-schema#label |
zafirlukast
|
| gptkbp:interactsWith |
gptkb:theophylline
gptkb:warfarin gptkb:erythromycin |
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
leukotriene D4 receptor antagonist
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
575.7 g/mol
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:proteinBinding |
>99%
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
headache liver dysfunction |
| gptkbp:usedFor |
asthma
|
| gptkbp:bfsParent |
gptkb:CYP2C8
|
| gptkbp:bfsLayer |
6
|