Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
xanthine oxidoreductase
|
| gptkbp:associatedWith |
gptkb:xanthinuria
|
| gptkbp:catalyzes |
oxidation of hypoxanthine to xanthine
oxidation of xanthine to uric acid |
| gptkbp:cofactor |
gptkb:FAD
molybdenum NAD+ iron-sulfur cluster |
| gptkbp:convertedTo |
gptkb:xanthine_oxidase
|
| gptkbp:EC_number |
1.17.1.4
|
| gptkbp:expressedIn |
liver
intestine |
| gptkbp:foundIn |
many organisms
|
| gptkbp:gene |
gptkb:XDH
|
| gptkbp:GO_term |
GO:0004854
|
| https://www.w3.org/2000/01/rdf-schema#label |
xanthine dehydrogenase
|
| gptkbp:inhibitedBy |
allopurinol
|
| gptkbp:involves |
purine metabolism
|
| gptkbp:locatedIn |
cytosol
|
| gptkbp:molecularWeight |
~150 kDa
|
| gptkbp:PDB |
1FO4
|
| gptkbp:product |
gptkb:NADH
gptkb:H2O2 uric acid |
| gptkbp:relatedTo |
gptkb:xanthine_oxidase
|
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:hypoxanthine
gptkb:xanthine |
| gptkbp:UniProtID |
P47989 (human)
|
| gptkbp:bfsParent |
gptkb:XDH
|
| gptkbp:bfsLayer |
7
|