Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:menaquinone
gptkb:vitamin_A |
| gptkbp:approvedBy |
food fortification
|
| gptkbp:ATCCode |
B02BA02
|
| gptkbp:biosynthesized_from |
intestinal bacteria
|
| gptkbp:CASNumber |
11032-49-8 (MK-7)
|
| gptkbp:chemicalFormula |
C46H64O2 (for MK-7)
|
| gptkbp:deficiencyCauses |
gptkb:bone
increased bleeding risk arterial calcification |
| gptkbp:discoveredBy |
gptkb:Henrik_Dam
|
| gptkbp:fatSoluble |
true
|
| gptkbp:foundIn |
gptkb:natto
animal products fermented foods |
| gptkbp:halfLife |
up to 72 hours (MK-7)
|
| gptkbp:hasEINECSNumber |
234-264-5 (MK-7)
|
| gptkbp:hasInChIKey |
MUMFZOSZBPTKQZ-DCBBRINESA-N (MK-7)
|
| gptkbp:hasRole |
cofactor for gamma-glutamyl carboxylase
|
| gptkbp:hasSMILES |
CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC1=CC(=O)C2=CC=CC=C2C1=O (MK-7)
|
| gptkbp:hasUNII |
8TTZ5Z7S6M (MK-7)
|
| https://www.w3.org/2000/01/rdf-schema#label |
vitamin K2 (menaquinone)
|
| gptkbp:IUPACName |
2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35-nonamethyldeca-2,6,10,14,18,22,26,30,34-nonaenyl]-1,4-naphthoquinone (MK-9)
|
| gptkbp:KEGGID |
C15602 (MK-7)
|
| gptkbp:MeSH_ID |
D017366
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
649.0 g/mol (MK-7)
|
| gptkbp:notSynthesizedBy |
plants
|
| gptkbp:producedBy |
bacteria in the human gut
|
| gptkbp:PubChem_CID |
DB01022
4444442 (MK-7) 5280483 (MK-7) CHEBI:75231 (MK-7) |
| gptkbp:regulates |
activation of matrix Gla-protein
activation of osteocalcin calcium metabolism |
| gptkbp:relatedTo |
vitamin K1 (phylloquinone)
|
| gptkbp:requires |
bone health
cardiovascular health blood clotting |
| gptkbp:solubility |
insoluble in water
soluble in fats and oils |
| gptkbp:subspecies |
gptkb:vitamin_A
gptkb:menaquinone-4_(MK-4) gptkb:menaquinone-7_(MK-7) gptkb:menaquinone-9_(MK-9) |
| gptkbp:usedAs |
dietary supplement
|
| gptkbp:usedFor |
osteoporosis prevention
cardiovascular disease prevention |
| gptkbp:bfsParent |
gptkb:menadione_(K3)
|
| gptkbp:bfsLayer |
5
|