Statements (32)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | gptkb:drug gptkb:monoclonal_antibody | 
| gptkbp:approvalYear | 2014 | 
| gptkbp:approvedBy | gptkb:FDA gptkb:EMA | 
| gptkbp:ATCCode | L04AA33 | 
| gptkbp:brand | gptkb:Entyvio | 
| gptkbp:CASNumber | 943609-66-3 | 
| gptkbp:developer | gptkb:Takeda_Pharmaceutical_Company | 
| gptkbp:drugClass | gptkb:immunosuppressant | 
| gptkbp:form | solution for infusion | 
| gptkbp:halfLife | 25 days | 
| gptkbp:KEGGID | D09913 | 
| gptkbp:legalStatus | prescription only | 
| gptkbp:mechanismOfAction | integrin α4β7 antagonist | 
| gptkbp:molecularWeight | 147 kDa | 
| gptkbp:pregnancyCategory | B (US) | 
| gptkbp:PubChem_CID | DB09033 CHEMBL1743026 | 
| gptkbp:routeOfAdministration | intravenous | 
| gptkbp:sideEffect | fever nausea headache arthralgia upper respiratory tract infection | 
| gptkbp:target | integrin α4β7 | 
| gptkbp:UNII | 6B4YK2V4U4 | 
| gptkbp:usedFor | gptkb:Crohn's_disease ulcerative colitis | 
| gptkbp:bfsParent | gptkb:alpha-4_beta-7_integrin | 
| gptkbp:bfsLayer | 7 | 
| https://www.w3.org/2000/01/rdf-schema#label | vedolizumab |