|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:activities
|
integrin inhibitor
|
|
gptkbp:appointed_by
|
intravenous infusion
|
|
gptkbp:approves
|
gptkb:United_States
|
|
gptkbp:clinical_trial
|
ongoing
completed
Phase III
chronic inflammatory bowel disease
|
|
gptkbp:competitors
|
other biologics
|
|
gptkbp:contraindication
|
active infections
hypersensitivity to vedolizumab
|
|
gptkbp:defense_mechanism
|
possible
|
|
gptkbp:dissolved
|
possible
|
|
gptkbp:dosage_form
|
solution for infusion
|
|
gptkbp:education
|
important
|
|
gptkbp:effective_date
|
2014-05-20
|
|
gptkbp:feedback
|
generally positive
|
|
gptkbp:formulation
|
sterile solution
|
|
gptkbp:frequency
|
every 8 weeks after initial doses
|
|
gptkbp:healthcare
|
gptkb:battle
injectable
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Entyvio
|
|
gptkbp:indication
|
moderate to severe ulcerative colitis
moderate to severe Crohn's disease
|
|
gptkbp:ingredients
|
vedolizumab
|
|
gptkbp:interacts_with
|
limited
|
|
gptkbp:is_atype_of
|
L04 A A29
|
|
gptkbp:is_monitored_by
|
liver function tests
infection signs
|
|
gptkbp:is_used_for
|
gptkb:Crohn's_disease
gptkb:ulcerative_colitis
|
|
gptkbp:label
|
includes warnings
|
|
gptkbp:manager
|
IV
|
|
gptkbp:manufacturer
|
gptkb:Takeda_Pharmaceutical_Company
|
|
gptkbp:marketed_as
|
multiple countries
|
|
gptkbp:pharmacokinetics
|
long half-life
selectively targets gut lymphocytes
|
|
gptkbp:population
|
adults
pediatric patients
|
|
gptkbp:price
|
high
|
|
gptkbp:provides_information_on
|
included in treatment guidelines
|
|
gptkbp:requires
|
gptkb:theorem
|
|
gptkbp:research
|
ongoing
|
|
gptkbp:research_focus
|
IBD treatment
|
|
gptkbp:safety_features
|
generally well tolerated
|
|
gptkbp:sales
|
increasing
|
|
gptkbp:scholarships
|
gptkb:stock_market_index
|
|
gptkbp:side_effect
|
fatigue
headache
nausea
abdominal pain
infusion-related reactions
serious infections
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:symbolism
|
gptkb:battle
|
|
gptkbp:traded_on
|
gptkb:Entyvio
|
|
gptkbp:type_of_insurance
|
varies by plan
|
|
gptkbp:bfsParent
|
gptkb:Genzyme_Genetics
|
|
gptkbp:bfsLayer
|
5
|