|
gptkbp:instanceOf
|
gptkb:virus
|
|
gptkbp:antigenicRelation
|
cross-protective against variola virus
|
|
gptkbp:biosafetyLevel
|
gptkb:BSL-2
|
|
gptkbp:causesDisease
|
gptkb:vaccinia
|
|
gptkbp:discoveredBy
|
18th century
|
|
gptkbp:entryMechanism
|
fusion with host cell membrane
|
|
gptkbp:enveloped
|
true
|
|
gptkbp:family
|
gptkb:Poxviridae
|
|
gptkbp:firstVaccineUse
|
gptkb:Edward_Jenner
|
|
gptkbp:genomeSize
|
~190 kbp
|
|
gptkbp:genomeType
|
double-stranded DNA
|
|
gptkbp:genus
|
gptkb:Orthopoxvirus
|
|
gptkbp:hostedBy
|
gptkb:livestock
humans
other mammals
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
vaccinia virus
|
|
gptkbp:notableStrain
|
gptkb:Copenhagen
gptkb:Ankara_(MVA)
gptkb:Western_Reserve
gptkb:Lister
|
|
gptkbp:proteinCodingGenes
|
~200
|
|
gptkbp:relatedTo
|
gptkb:variola_virus
gptkb:cowpox_virus
gptkb:monkeypox_virus
|
|
gptkbp:replicationCycle
|
cytoplasmic
|
|
gptkbp:replicationSite
|
gptkb:cytoplasm
|
|
gptkbp:shape
|
brick-shaped
|
|
gptkbp:size
|
approximately 360 x 270 x 250 nm
|
|
gptkbp:transmission
|
direct contact
inoculation
|
|
gptkbp:usedFor
|
smallpox vaccine
|
|
gptkbp:usedIn
|
oncolytic virus therapy
recombinant vaccine development
|
|
gptkbp:vaccineDiscontinued
|
1980s (routine use)
|
|
gptkbp:vaccineType
|
live attenuated
|
|
gptkbp:WHOStatus
|
used in smallpox eradication
|
|
gptkbp:bfsParent
|
gptkb:Variola_virus
|
|
gptkbp:bfsLayer
|
5
|