Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
rare disease |
| gptkbp:affects |
adults
children |
| gptkbp:alsoKnownAs |
oncogenic osteomalacia
|
| gptkbp:causedBy |
overproduction of FGF23
phosphaturic mesenchymal tumor |
| gptkbp:characterizedBy |
gptkb:osteomalacia
muscle weakness bone pain hypophosphatemia |
| gptkbp:diagnosedBy |
imaging studies
biochemical tests |
| gptkbp:field |
oncology
endocrinology |
| gptkbp:firstDescribed |
1947
|
| gptkbp:hasBiomarker |
low serum phosphate
elevated FGF23 low 1,25-dihydroxyvitamin D |
| https://www.w3.org/2000/01/rdf-schema#label |
tumor-induced osteomalacia
|
| gptkbp:symptom |
fatigue
fractures difficulty walking |
| gptkbp:treatableBy |
surgical removal of tumor
|
| gptkbp:treatment |
active vitamin D analogs
phosphate supplements |
| gptkbp:bfsParent |
gptkb:FGF23
gptkb:Crysvita |
| gptkbp:bfsLayer |
8
|