Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
alkaloid muscle relaxant |
| gptkbp:antidote |
gptkb:neostigmine
gptkb:edrophonium |
| gptkbp:ATCCode |
M03AA01
|
| gptkbp:CASNumber |
57-94-3
|
| gptkbp:category |
quaternary ammonium compound
benzylisoquinoline alkaloid peripheral muscle relaxant |
| gptkbp:chemicalFormula |
C37H41N2O6+
|
| gptkbp:component |
curare
|
| gptkbp:discoveredBy |
gptkb:Harold_King
|
| gptkbp:discoveredIn |
1935
|
| gptkbp:foundIn |
gptkb:Chondrodendron_tomentosum
|
| gptkbp:hasSMILES |
COc1ccc2c(c1)C3CCN4CCc5c6c(ccc(c6ccc5C4CCN3C2)OC)OC
|
| https://www.w3.org/2000/01/rdf-schema#label |
tubocurarine
|
| gptkbp:IUPACName |
(1β)-1,2,3,4,6,7,8,12-octahydro-1,6,7,12-tetramethoxy-2,5,11,14-tetramethyl-9,10:13,15-dimetheno-1H,5H,11H,15H-[1,3]dioxolo[4,5-g][1,3]dioxolo[4',5':6,7]indolo[2,3-a]quinolizine
|
| gptkbp:legalStatus |
withdrawn in many countries
|
| gptkbp:mechanismOfAction |
nicotinic acetylcholine receptor antagonist
|
| gptkbp:meltingPoint |
178 °C
|
| gptkbp:MeSH_ID |
D014047
|
| gptkbp:molecularWeight |
609.73 g/mol
|
| gptkbp:origin |
South American plants
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL1201202
60900 CHEBI:9647 DB01161 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
hypotension
respiratory paralysis histamine release |
| gptkbp:solubility |
water soluble
|
| gptkbp:synonym |
gptkb:d-tubocurarine
gptkb:tubocurarinum |
| gptkbp:UNII |
QX9Y1K1W0F
|
| gptkbp:used_in |
surgery
general anesthesia |
| gptkbp:usedFor |
neuromuscular-blocking drug
|
| gptkbp:bfsParent |
gptkb:Menispermaceae
|
| gptkbp:bfsLayer |
6
|