tubocurarine

URI: https://gptkb.org/entity/tubocurarine

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:chemical_compound gptkb:muscle_relaxant gptkb:alkaloid
gptkbp:antidote	gptkb:neostigmine gptkb:edrophonium
gptkbp:ATCCode	M03AA01
gptkbp:CASNumber	57-94-3
gptkbp:category	gptkb:quaternary_ammonium_compound benzylisoquinoline alkaloid peripheral muscle relaxant
gptkbp:chemicalFormula	C37H41N2O6+
gptkbp:component	curare
gptkbp:discoveredBy	gptkb:Harold_King
gptkbp:discoveredIn	1935
gptkbp:foundIn	gptkb:Chondrodendron_tomentosum
gptkbp:hasSMILES	COc1ccc2c(c1)C3CCN4CCc5c6c(ccc(c6ccc5C4CCN3C2)OC)OC
gptkbp:IUPACName	(1β)-1,2,3,4,6,7,8,12-octahydro-1,6,7,12-tetramethoxy-2,5,11,14-tetramethyl-9,10:13,15-dimetheno-1H,5H,11H,15H-[1,3]dioxolo[4,5-g][1,3]dioxolo[4',5':6,7]indolo[2,3-a]quinolizine
gptkbp:legalStatus	withdrawn in many countries
gptkbp:mechanismOfAction	nicotinic acetylcholine receptor antagonist
gptkbp:meltingPoint	178 °C
gptkbp:MeSH_ID	D014047
gptkbp:molecularWeight	609.73 g/mol
gptkbp:origin	South American plants
gptkbp:PubChem_CID	gptkb:CHEMBL1201202 60900 CHEBI:9647 DB01161
gptkbp:routeOfAdministration	intravenous
gptkbp:sideEffect	hypotension respiratory paralysis histamine release
gptkbp:solubility	water soluble
gptkbp:synonym	gptkb:d-tubocurarine gptkb:tubocurarinum
gptkbp:UNII	QX9Y1K1W0F
gptkbp:used_in	surgery general anesthesia
gptkbp:usedFor	gptkb:neuromuscular-blocking_drug
gptkbp:bfsParent	gptkb:Menispermaceae
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	tubocurarine