d-tubocurarine

URI: https://gptkb.org/entity/d-tubocurarine
GPTKB entity
Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
alkaloid
gptkbp:antidote gptkb:acetylcholinesterase_inhibitor
gptkbp:ATCCode M03BA01
gptkbp:CASNumber 57-94-3
gptkbp:category quaternary ammonium compound
benzylisoquinoline alkaloid
neuromuscular-blocking drug
gptkbp:chemicalFormula C37H41N2O6+
gptkbp:discoveredBy gptkb:Harold_King
gptkbp:eliminationHalfLife 1.5–2.5 hours
gptkbp:foundIn gptkb:Chondrodendron_tomentosum
https://www.w3.org/2000/01/rdf-schema#label d-tubocurarine
gptkbp:IUPACName (1β)-1,2,3,4,4a,5,6,7,8,9,10,11,12,13,14,15-hexadecahydro-1,5,9,13-tetraazacyclooctadecin-16,18-dione
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction nicotinic acetylcholine receptor antagonist
gptkbp:medicalUse adjunct to anesthesia
facilitate endotracheal intubation
gptkbp:molecularWeight 609.73 g/mol
gptkbp:origin plant-derived
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect hypotension
histamine release
gptkbp:synonym gptkb:tubocurarine
gptkbp:usedAs muscle relaxant
gptkbp:usedIn surgery
gptkbp:bfsParent gptkb:tubocurarine
gptkbp:bfsLayer 7