Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
conversion of indole and serine to tryptophan
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:discoveredBy |
1950s
|
| gptkbp:EC_number |
4.2.1.20
|
| gptkbp:foundIn |
gptkb:Bacteria
fungi plants |
| gptkbp:gene_symbol_(E._coli) |
gptkb:trpA
gptkb:trpB |
| gptkbp:has_industrial_use |
biocatalysis
amino acid production |
| https://www.w3.org/2000/01/rdf-schema#label |
tryptophan synthase
|
| gptkbp:inhibitedBy |
tryptophan (feedback inhibition)
|
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:molecular_weight_(E._coli) |
~145 kDa
|
| gptkbp:pathway |
tryptophan biosynthesis
|
| gptkbp:PDB |
1KFC
|
| gptkbp:product |
gptkb:water
L-tryptophan |
| gptkbp:structure |
heterotetramer (α2β2)
|
| gptkbp:substrate |
gptkb:L-serine
gptkb:indole |
| gptkbp:subunit |
alpha and beta subunits
|
| gptkbp:type |
lyase
|
| gptkbp:bfsParent |
gptkb:pyridoxal_phosphate
|
| gptkbp:bfsLayer |
7
|