triple-negative breast cancer

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf breast cancer subtype
gptkbp:associatedWith gptkb:BRCA1_mutation
gptkbp:characterizedBy aggressive clinical behavior
high grade tumors
gptkbp:has_higher_prevalence_in patients with BRCA1 mutations
gptkbp:has_higher_risk_of recurrence
gptkbp:has_poor_prognosis_compared_to other breast cancer subtypes
https://www.w3.org/2000/01/rdf-schema#label triple-negative breast cancer
gptkbp:is_a_focus_of ongoing clinical research
gptkbp:is_diagnosed_by immunohistochemistry
gptkbp:is_more_common_in African American women
younger women
gptkbp:is_not_treated_with hormone therapy
HER2-targeted therapy
gptkbp:is_treated_with chemotherapy
gptkbp:lacks_expression_of gptkb:HER2_protein
estrogen receptor
progesterone receptor
gptkbp:treatment immunotherapy
PARP inhibitors
gptkbp:type gptkb:invasive_ductal_carcinoma
gptkbp:bfsParent gptkb:Keytruda
gptkbp:bfsLayer 5