triple-negative breast cancer
GPTKB entity
Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
breast cancer subtype
|
gptkbp:associatedWith |
gptkb:BRCA1_mutation
|
gptkbp:characterizedBy |
aggressive clinical behavior
high grade tumors |
gptkbp:has_higher_prevalence_in |
patients with BRCA1 mutations
|
gptkbp:has_higher_risk_of |
recurrence
|
gptkbp:has_poor_prognosis_compared_to |
other breast cancer subtypes
|
https://www.w3.org/2000/01/rdf-schema#label |
triple-negative breast cancer
|
gptkbp:is_a_focus_of |
ongoing clinical research
|
gptkbp:is_diagnosed_by |
immunohistochemistry
|
gptkbp:is_more_common_in |
African American women
younger women |
gptkbp:is_not_treated_with |
hormone therapy
HER2-targeted therapy |
gptkbp:is_treated_with |
chemotherapy
|
gptkbp:lacks_expression_of |
gptkb:HER2_protein
estrogen receptor progesterone receptor |
gptkbp:treatment |
immunotherapy
PARP inhibitors |
gptkbp:type |
gptkb:invasive_ductal_carcinoma
|
gptkbp:bfsParent |
gptkb:Keytruda
|
gptkbp:bfsLayer |
5
|