translocation t(14;18)(q32;q21)
GPTKB entity
Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chromosomal band
|
| gptkbp:associatedWith |
diffuse large B-cell lymphoma
follicular lymphoma |
| gptkbp:breakpointLocation |
14q32
18q21 |
| gptkbp:chromosomeInvolved |
gptkb:chromosome_14
gptkb:chromosome_18 |
| gptkbp:detects |
gptkb:FISH
PCR |
| gptkbp:effect |
overexpression of BCL2
|
| gptkbp:frequencyInFollicularLymphoma |
~85%
|
| https://www.w3.org/2000/01/rdf-schema#label |
translocation t(14;18)(q32;q21)
|
| gptkbp:involvedIn |
gptkb:BCL2
gptkb:IGH |
| gptkbp:mechanismOfAction |
juxtaposition of BCL2 to IGH enhancer
|
| gptkbp:bfsParent |
gptkb:BCL2_gene
|
| gptkbp:bfsLayer |
8
|