toxic shock syndrome toxin-1 (TSST-1)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
bacterial exotoxin
|
| gptkbp:associatedWith |
gptkb:toxic_shock_syndrome
|
| gptkbp:binds |
gptkb:MHC_class_II_molecules
gptkb:T-cell_receptor_Vβ_region |
| gptkbp:cause |
fever
rash hypotension multi-organ dysfunction |
| gptkbp:discoveredIn |
1981
|
| gptkbp:encodedBy |
gptkb:tst_gene
|
| gptkbp:foundIn |
tampon-associated infections
|
| https://www.w3.org/2000/01/rdf-schema#label |
toxic shock syndrome toxin-1 (TSST-1)
|
| gptkbp:inducedBy |
massive cytokine release
|
| gptkbp:mechanismOfAction |
superantigen
|
| gptkbp:molecularWeight |
22 kDa
|
| gptkbp:producedBy |
gptkb:Staphylococcus_aureus
|
| gptkbp:promotion |
gptkb:T_cells
|
| gptkbp:significance |
gptkb:menstrual_toxic_shock_syndrome
gptkb:non-menstrual_toxic_shock_syndrome |
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:thermalStability |
heat-stable
|
| gptkbp:bfsParent |
gptkb:Staphylococcus_aureus_subsp._aureus_Rosenbach
|
| gptkbp:bfsLayer |
6
|