tolloid proteases

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:catalyzes cleavage of chordin
cleavage of procollagen
gptkbp:cofactor zinc
gptkbp:contains Bone morphogenetic protein 1 (BMP1)
Mammalian Tolloid (mTLD)
Tolloid-like 1 (TLL1)
Tolloid-like 2 (TLL2)
gptkbp:discoveredIn gptkb:Drosophila_melanogaster
gptkbp:EC_number 3.4.24.-
gptkbp:foundIn animals
gptkbp:function extracellular matrix remodeling
metalloprotease activity
gptkbp:GO_term GO:0004222 (metalloendopeptidase activity)
GO:0006508 (proteolysis)
https://www.w3.org/2000/01/rdf-schema#label tolloid proteases
gptkbp:memberOf metzincin superfamily
gptkbp:orthologIn Drosophila tolloid
gptkbp:relatedTo gptkb:bone_morphogenetic_proteins
gptkbp:role embryonic development
dorsoventral patterning
gptkbp:bfsParent gptkb:chordin
gptkbp:bfsLayer 7