Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:alsoKnownAs |
gptkb:thiazolidinediones
|
| gptkbp:compatibleWith |
type 1 diabetes
|
| gptkbp:contraindication |
heart failure
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:effect |
increase insulin sensitivity
|
| gptkbp:example |
gptkb:pioglitazone
gptkb:rosiglitazone |
| https://www.w3.org/2000/01/rdf-schema#label |
glitazones
|
| gptkbp:mechanismOfAction |
PPAR-gamma agonist
|
| gptkbp:regulates |
lipid metabolism
prescription only glucose metabolism insulin sensitivity adipocyte differentiation |
| gptkbp:riskFactor |
bone fracture
bladder cancer (pioglitazone) |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
weight gain
fluid retention risk of heart failure |
| gptkbp:usedFor |
gptkb:type_2_diabetes
|
| gptkbp:bfsParent |
gptkb:thiazolidinediones
|
| gptkbp:bfsLayer |
7
|