succinate dehydrogenase complex (complex II)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:alternativeName	gptkb:SDH gptkb:complex_II gptkb:succinate-coenzyme_Q_reductase
gptkbp:catalyzes	succinate to fumarate
gptkbp:cofactor	gptkb:FAD gptkb:heme_b iron-sulfur clusters
gptkbp:discoveredBy	gptkb:Albert_Szent-Györgyi
gptkbp:EC_number	1.3.5.1
gptkbp:foundIn	prokaryotes eukaryotes
gptkbp:function	oxidation of succinate reduction of ubiquinone
gptkbp:gene	gptkb:SDHA gptkb:SDHB gptkb:SDHC gptkb:SDHD
gptkbp:GO_term	GO:0000104
gptkbp:hasActivity	succinate dehydrogenase activity ubiquinone oxidoreductase activity
gptkbp:hasComponent	gptkb:SDHA gptkb:SDHB gptkb:SDHC gptkb:SDHD
https://www.w3.org/2000/01/rdf-schema#label	succinate dehydrogenase complex (complex II)
gptkbp:inhibitedBy	gptkb:thenoyltrifluoroacetone malonate
gptkbp:locatedIn	inner mitochondrial membrane
gptkbp:mutationAssociatedWith	gptkb:Leigh_syndrome gptkb:pheochromocytoma paraganglioma
gptkbp:OMIM	600857
gptkbp:partOf	electron transport chain citric acid cycle
gptkbp:PDB	gptkb:2H88 1ZOY
gptkbp:requires	aerobic respiration
gptkbp:subcellularLocation	mitochondrion
gptkbp:UniProtID	Q967F6
gptkbp:bfsParent	gptkb:SDHA
gptkbp:bfsLayer	7