|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alsoKnownAs
|
gptkb:succinate_dehydrogenase
gptkb:succinate-coenzyme_Q_reductase
|
|
gptkbp:cofactor
|
gptkb:FAD
gptkb:heme_b
iron-sulfur clusters
|
|
gptkbp:component
|
electron transport chain
mitochondrial inner membrane
|
|
gptkbp:discoveredBy
|
gptkb:Albert_Szent-Györgyi
|
|
gptkbp:discoveredIn
|
1937
|
|
gptkbp:EC_number
|
1.3.5.1
|
|
gptkbp:foundIn
|
prokaryotes
eukaryotes
|
|
gptkbp:function
|
catalyzes oxidation of succinate to fumarate
reduces ubiquinone to ubiquinol
|
|
gptkbp:gene
|
gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
|
|
gptkbp:GO
|
GO:0008177
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Complex II
|
|
gptkbp:inhibitedBy
|
gptkb:thenoyltrifluoroacetone
gptkb:carboxin
malonate
|
|
gptkbp:location
|
mitochondrial inner membrane
|
|
gptkbp:molecularWeight
|
~140 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Leigh_syndrome
gptkb:pheochromocytoma
paraganglioma
|
|
gptkbp:OMIM
|
600857
|
|
gptkbp:PDB
|
1ZOY
|
|
gptkbp:role
|
gptkb:Krebs_cycle
oxidative phosphorylation
|
|
gptkbp:subunit
|
gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
|
|
gptkbp:UniProtID
|
Q967G5
|
|
gptkbp:bfsParent
|
gptkb:Electron_Transport_Chain
gptkb:succinate_dehydrogenase_complex
|
|
gptkbp:bfsLayer
|
8
|