Statements (38)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
signaling molecule
bioactive lipid |
| gptkbp:binds |
S1P receptor 1
S1P receptor 2 S1P receptor 3 S1P receptor 4 S1P receptor 5 |
| gptkbp:CASNumber |
26993-30-6
|
| gptkbp:chemicalFormula |
C18H38NO5P
|
| gptkbp:derivedFrom |
gptkb:sphingosine
|
| gptkbp:foundIn |
lymph
blood plasma tissues |
| gptkbp:heldBy |
lipoprotein
sphingolipid metabolite |
| https://www.w3.org/2000/01/rdf-schema#label |
sphingosine-1-phosphate
|
| gptkbp:involves |
inflammation
vascular maturation lymphocyte egress |
| gptkbp:is_degraded_by |
S1P lyase
|
| gptkbp:producedBy |
sphingosine kinase
|
| gptkbp:regulates |
cell survival
angiogenesis cell growth immune cell trafficking |
| gptkbp:role |
gptkb:cardiovascular_disease
cancer biology autoimmune disease multiple sclerosis therapy |
| gptkbp:target |
gptkb:ozanimod
gptkb:siponimod gptkb:fingolimod S1P receptor modulators ponesimod |
| gptkbp:bfsParent |
gptkb:sphingosine-1-phosphate_receptor_1
gptkb:sphingosine-1-phosphate_receptor_4 gptkb:sphingosine-1-phosphate_receptor_5 |
| gptkbp:bfsLayer |
7
|