Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
DNA clamp
processivity factor |
| gptkbp:binds |
gptkb:gene
DNA polymerase |
| gptkbp:component |
DNA replication
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
PCNA gene (eukaryotes)
dnaN gene (E. coli) |
| gptkbp:example |
gptkb:PCNA
beta clamp |
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
increases DNA polymerase processivity
|
| https://www.w3.org/2000/01/rdf-schema#label |
sliding clamp
|
| gptkbp:molecularWeight |
~29 kDa (PCNA monomer)
~40 kDa (beta clamp monomer) |
| gptkbp:requires |
DNA synthesis
clamp loader |
| gptkbp:shape |
ring-shaped
|
| gptkbp:structure |
homodimer (beta clamp)
homotrimer (PCNA) |
| gptkbp:bfsParent |
gptkb:DNA_polymerase_holoenzyme
|
| gptkbp:bfsLayer |
7
|