sigma-54

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf transcription factor
gptkbp:activatorProteinsInclude gptkb:DctD
gptkb:NtrC
gptkb:PspF
gptkbp:alternativeName gptkb:σ54
gptkb:RpoN
gptkbp:compatibleWith most Gram-positive bacteria
gptkbp:doesNotRecognize -35/-10 promoter elements
gptkbp:EC_number 2.7.7.6 (as part of RNA polymerase holoenzyme)
gptkbp:encodedBy rpoN gene
gptkbp:features requires ATP hydrolysis for open complex formation
gptkbp:firstDescribed 1980s
gptkbp:foundIn gptkb:Bacteria
gptkbp:function transcription initiation
regulation of nitrogen metabolism
https://www.w3.org/2000/01/rdf-schema#label sigma-54
gptkbp:interactsWith bacterial RNA polymerase core enzyme
gptkbp:presentIn gptkb:Salmonella_enterica
gptkb:Vibrio_cholerae
gptkb:Pseudomonas_aeruginosa
gptkb:Bacteria
gptkbp:recognizedPromoterSequence -24/-12 promoter elements
gptkbp:regulates flagellar biosynthesis genes
genes involved in nitrogen assimilation
virulence genes in some bacteria
gptkbp:requires activator proteins
gptkbp:structuralDomain three conserved regions
gptkbp:bfsParent gptkb:transcription_factor
gptkbp:bfsLayer 6