retinol dehydrogenase 12

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:associatedWith gptkb:Leber_congenital_amaurosis
retinitis pigmentosa
gptkbp:biologicalProcess NADP-retinol dehydrogenase activity
gptkbp:catalyzes oxidation of all-trans-retinol to all-trans-retinal
gptkbp:EC_number 1.1.1.105
gptkbp:expressedIn gptkb:kidney
retina
liver
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function oxidoreductase activity
retinol dehydrogenase activity
gptkbp:gene RDH12
gptkbp:HGNC_ID 18267
gptkbp:locatedOnChromosome chromosome 14q24.1
gptkbp:location gptkb:endoplasmic_reticulum
gptkbp:mutationAssociatedWith causes early-onset severe retinal dystrophy
gptkbp:OMIM 608830
gptkbp:UniProtID Q96NR8
gptkbp:bfsParent gptkb:RDH12_gene
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label retinol dehydrogenase 12