rasburicase

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkb:enzyme
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
2002
gptkbp:ATCCode V03AF07
gptkbp:brand Elitek
Fasturtec
gptkbp:CASNumber 133639-02-6
gptkbp:contraindication gptkb:G6PD_deficiency
https://www.w3.org/2000/01/rdf-schema#label rasburicase
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction catalyzes oxidation of uric acid to allantoin
gptkbp:molecularWeight 34 kDa
gptkbp:origin recombinant DNA technology
gptkbp:producedBy Aspergillus flavus (recombinant)
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect allergic reactions
hemolysis in G6PD deficiency
gptkbp:target uric acid
gptkbp:UNII Q10KZ7A4F7
gptkbp:usedFor gptkb:tumor_lysis_syndrome
treatment of hyperuricemia
gptkbp:bfsParent gptkb:tumor_lysis_syndrome
gptkbp:bfsLayer 6