Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
combination drug |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
J01FG
|
| gptkbp:brand |
Synercid
|
| gptkbp:contains |
dalfopristin
quinupristin |
| gptkbp:discoveredBy |
gptkb:Aventis
|
| gptkbp:drugClass |
streptogramin
|
| gptkbp:eliminationHalfLife |
0.7 hours (dalfopristin)
0.85 hours (quinupristin) |
| https://www.w3.org/2000/01/rdf-schema#label |
quinupristin-dalfopristin
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
protein synthesis inhibitor
|
| gptkbp:metabolism |
liver
|
| gptkbp:notEffectiveAgainst |
gptkb:Enterococcus_faecalis
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
rash pain at injection site arthralgia myalgia |
| gptkbp:spectrumOfActivity |
Gram-positive bacteria
|
| gptkbp:usedFor |
bacterial infections
vancomycin-resistant Enterococcus faecium |
| gptkbp:bfsParent |
gptkb:VRSA
|
| gptkbp:bfsLayer |
7
|