pyruvate dehydrogenase (PDH)
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:pyruvate
gptkb:ADP Ca2+ |
| gptkbp:alternativeName |
PDH E1
pyruvate dehydrogenase E1 |
| gptkbp:catalyzes |
conversion of pyruvate to acetyl-CoA
|
| gptkbp:cofactor |
gptkb:Coenzyme_A
gptkb:FAD NAD+ lipoic acid thiamine pyrophosphate (TPP) |
| gptkbp:component |
pyruvate dehydrogenase complex (PDC)
|
| gptkbp:deficiencyCauses |
lactic acidosis
|
| gptkbp:EC_number |
1.2.4.1
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:gene |
gptkb:PDHA2
gptkb:PDHB gptkb:PDHA1 |
| https://www.w3.org/2000/01/rdf-schema#label |
pyruvate dehydrogenase (PDH)
|
| gptkbp:inhibitedBy |
gptkb:NADH
acetyl-CoA |
| gptkbp:participatedIn |
aerobic respiration
citric acid cycle entry link reaction |
| gptkbp:regulates |
phosphorylation
dephosphorylation |
| gptkbp:subunit |
E1 component of PDC
|
| gptkbp:bfsParent |
gptkb:PDK2
|
| gptkbp:bfsLayer |
7
|